Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. . Activation of TPO-R leads to the ....
Eltrombopag, sold under the brand name Promacta among others, is a medication used to treat thrombocytopenia (abnormally low platelet counts) and severe aplastic anemia. Promacta (eltrombopag) is known as Revolade® outside the U.S. and is marketed worldwide by Novartis.. It is a thrombopoietin receptor agonist. Eltrombopag was discovered as a result of research collaboration between ....
Eltrombopag olamine, equivalent to 25 mg or 50 mg of eltrombopag free acid. (3) ... • Eltrombopag is an inhibitor of OATP1B1 transporter. ... 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action 12.2 Pharmacodynamics 12.3 Pharmacokinetics.
Revolade. Active Substance: eltrombopag olamine Common Name: eltrombopag ATC Code: B02BX05 Marketing Authorisation Holder: Novartis Europharm Limited Active Substance: eltrombopag olamine Status: Authorised Authorisation Date: 2010-03-11 Therapeutic Area: Purpura, Thrombocytopenic, Idiopathic Pharmacotherapeutic Group: Antihaemorrhagics Therapeutic Indication.
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This section contains a list of the policy recommendations of the Pan Mersey Area Prescribing Committee. Reviews of the new medicines have been conducted by our pharmacists using a number of resources including National Institute for Health and Clinical Excellence (NICE) which is a Special health Authority (SHA) set up in 1999..
Eltrombopag olamine eltrombopag tablets elvitegravir elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate table empagliflozin empagliflozin and linagliptin tablets empagliflozin tablets emtricitabine ... 7:11:38 pm other titles: priority monographs ....
2019-11-29: Talazoparib or its salts: 2019-11-29: Omeprazole or its salts: Omeprazole magnesium: except when sold for the 14-day treatment for frequent heartburn at a daily dose of 20 milligrams: 2016-12-19: Trifarotene or its salts: 2020-02-13: Gemtuzumab ozogamicin: 2020-02-13: Icosapent ethyl.
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